منابع مشابه
Creutzfeldt-Jakob disease: A case report
Background: Creutzfeldt-Jakob disease (CJD) as a life-threatening neurodegenerative disorder is not usually diagnosed in early stages of the disease because of a variety in its clinical manifestations. This study aimed to present a middle-aged woman with psychiatric symptoms who ultimately was diagnosed as a CJD case. Case presentation: This 48-year-old woman had progressive symptoms of depres...
متن کاملGenetic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease.
The ‘‘pulvinar sign’’ on MRI brain scan is defined as hyperintensity of the posterior thalamus relative to the signal intensity of the anterior putamen. In the appropriate clinical context, the pulvinar sign and hyperintensity in the dorsomedial thalamic nuclei (the hockey stick sign) are sensitive and specific features of variant Creutzfeldt– Jakob disease (vCJD). Variant CJD is an acquired fo...
متن کاملSporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease.
BACKGROUND The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons. OBJECTIVE To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging findings consistent with variant CJD (vCJD). RESULTS Results of a repeate...
متن کاملIntroducing Worm
In 1963 Sydney Brenner proposed to study the development of multi-cellular organisms using a genetic approach in a simple animal. He settled on a small, transparent nematode, Caenorhabditis elegans, which develops quickly and is anatomically simple with less than a thousand somatic cells. Almost half a century later there are many more researchers studying C. elegans than there are somatic cell...
متن کاملWorm sensation!
Mechanosensation plays a pivotal role in many aspects of pain pathology, yet the mammalian molecular transduction apparatus responsible for this sensory modality remains unknown. In January's edition of Nature Neuroscience, O'Hagan, Chalfie and Goodman [1] have provided direct electrophysiological evidence that somatic mechanotransduction in C. elegans is mediated by a complex of proteins previ...
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ژورنال
عنوان ژورنال: Skandinavisches Archiv Für Physiologie
سال: 1889
ISSN: 0370-839X
DOI: 10.1111/j.1748-1716.1889.tb00476.x